Hoʻopili antibacterial o ka cinnamaldehyde i loko o ka ʻōpala meaʻai

ʻO Cinnamaldehyde ka helu no 85% ~ 90% o ka ʻaila koʻikoʻi kinamona, a ʻo Kina kekahi o nā wahi kanu nui o ke kinamona, a waiwai nui nā kumuwaiwai cinnamaldehyde. ʻO ke ʻano molekala Cinnamaldehyde (C9H8O) he hui phenyl i pili i kahi acrylein, ma ke ʻano kūlohelohe o ka wai viscous melemele a melemele paha, me kahi ʻono kinamona a me ka coke kū hoʻokahi a ikaika, hiki ke hoʻohana ʻia i nā mea ʻala a me nā mea ʻono. I kēia manawa, ua nui nā hōʻike e pili ana i ka hana antibacterial ākea o ka cinnamaldehyde a me kāna ʻano hana, a ua hōʻike nā haʻawina he hopena antibacterial maikaʻi ko ka cinnamaldehyde i nā bacteria a me nā fungi. Ma ke kahua o ka lāʻau lapaʻau, ua nānā hou kekahi mau haʻawina i ka holomua o ka noiʻi o ka cinnamaldehyde i nā maʻi metabolic, nā maʻi ʻōnaehana circulatory, anti-tumor a me nā ʻano ʻē aʻe, a ua ʻike ʻia he anti-diabetes maikaʻi ko ka cinnamaldehyde, anti-obesity, anti-tumor a me nā hana pharmacological ʻē aʻe. Ma muli o kona mau kumu waiwai, nā mea kūlohelohe, ka palekana, ka haʻahaʻa o ka ʻawahia, ka ʻono kū hoʻokahi a me ka hopena antibacterial ākea, he mea hoʻohui meaʻai ia i ʻae ʻia e ka United States Food and Drug Administration a me Kina. ʻOiai ʻaʻole i kaupalena ʻia ka nui o ka hoʻohana ʻana, ʻo kona volatility a me ka ʻala pungent e kaupalena i kona hoʻohana ākea ʻana i ka meaʻai. ʻO ka hoʻopaʻa ʻana i ka cinnamaldehyde i loko o ka ʻili ʻōpala meaʻai hiki ke hoʻomaikaʻi i kona pono antibacterial a hoʻemi i kona hopena sensory i ka meaʻai, a pāʻani i kahi hana i ka hoʻomaikaʻi ʻana i ka maikaʻi o ka mālama ʻana a me ka lawe ʻana i ka meaʻai a me ka hoʻolōʻihi ʻana i ke ola papa.

1. Matrix membrane hui pū ʻia antibacterial

ʻO ka hapa nui o ka noiʻi ʻana i ka ʻili ʻōpala antibacterial o ka meaʻai e hoʻohana ana i nā mea kūlohelohe a me nā mea hiki ke palaho ma ke ʻano he matrix hana kiʻiʻoniʻoni, a ua hoʻomākaukau ʻia ka ʻili ʻōpala ma ke ʻano uhi, hoʻolei ʻana a i ʻole ke ʻano extrusion wela kiʻekiʻe. Ma muli o ke ʻano hana like ʻole a me ka hoʻohālikelike ma waena o nā substrates membrane like ʻole a me nā mea hana, ʻokoʻa nā waiwai o ka membrane i hoʻopau ʻia, no laila he mea nui loa ke koho ʻana i ka substrate membrane kūpono. ʻO nā substrates hana kiʻiʻoniʻoni i hoʻohana pinepine ʻia e komo pū me nā mea biodegradable synthetic e like me ka polyvinyl alcohol a me ka polypropylene, nā mea kūlohelohe e like me ka polysaccharides a me nā protein, a me nā mea hui. ʻO ka Polyvinyl alcohol (PVA) he polymer linear, kahi e hana pinepine ai i kahi ʻano pūnaewele ʻekolu-dimensional i ka wā e crosslinked ai, a he mau waiwai mechanical maikaʻi loa a me nā waiwai pale. He nui a he nui nā kumuwaiwai matrix e like me ka membrane kūlohelohe. No ka laʻana, hiki ke hoʻoulu ʻia ka waikawa polylactic mai nā mea maka e like me ka starch a me ka kulina, nona nā kumu lawa a hou hou, biodegradability maikaʻi a me ka biocompatibility, a he mea hoʻopili maikaʻi loa ia no ke kaiapuni. Hoʻohui pinepine ʻia ka matrix composite i ʻelua a ʻoi aku paha nā matrices membrane, hiki ke pāʻani i kahi hana hoʻohui i hoʻohālikelike ʻia me kahi matrix membrane hoʻokahi.

ʻO nā waiwai mechanical a me nā waiwai pale he mau hōʻailona koʻikoʻi ia e loiloi i ke kūpono o ka ʻili ʻōpala. ʻO ka hoʻohui ʻana o ka cinnamaldehyde e hoʻopili me ka matrix membrane polymer a pēlā e hōʻemi ai i ka fluidity molecular, ʻo ka emi ʻana o ka elongation i ka haki ʻana ma muli o ka discontinuity o ke ʻano pūnaewele polysaccharide, a ʻo ka hoʻonui ʻana o ka ikaika tensile ma muli o ka hoʻonui ʻana o ka hui hydrophilic i ka wā o ke kaʻina hana ʻili i hoʻokumu ʻia e ka hoʻohui ʻana o ka cinnamaldehyde. Eia kekahi, ua hoʻonui nui ʻia ka permeability kinoea o ka membrane composite cinnamaldehyde, hiki ke ma muli o ka hoʻopuehu ʻana o ka cinnamaldehyde i loko o ka polymer e hana i nā pores, nā voids a me nā kahawai, e hōʻemi i ke kū'ē ʻana o ka hoʻoili nui ʻana o nā molekala wai, a i ka hopena e alakaʻi ai i ka hoʻonui ʻana o ka permeability kinoea o ka membrane composite cinnamaldehyde. Ua like nā waiwai mechanical a me ka permeability o kekahi mau membrane composite, akā ʻokoʻa ke ʻano a me nā waiwai o nā substrates polymer like ʻole, a ʻo nā pilina like ʻole me ka cinnamaldehyde e hoʻopilikia i ka hana o ka ʻili ʻōpala, a laila e hoʻopilikia i kāna noi, no laila he mea nui loa ke koho ʻana i ka substrate polymer kūpono a me ka noʻonoʻo.

ʻO ka lua, cinnamaldehyde a me ke ʻano hoʻopaʻa ʻana i ka ʻili ʻili

Eia nō naʻe, ua hoʻoheheʻe iki ʻia ka cinnamaldehyde i ka wai me ka solubility o 1.4 mg/mL wale nō. ʻOiai he maʻalahi a kūpono hoʻi ka ʻenehana hoʻohuihui, ʻaʻole paʻa nā pae ʻelua o ka cinnamaldehyde momona-soluble a me ka matrix membrane wai-soluble, a ʻo ke kiʻekiʻe o ka mahana a me ke kaomi kiʻekiʻe e pono ai i ke kaʻina hana hana kiʻiʻoniʻoni e hōʻemi nui i ka nui o ka cinnamaldehyde i loaʻa i loko o ka membrane. He paʻakikī ke hoʻokō i ka hopena bacteriostatic kūpono. ʻO ka ʻenehana hoʻokomo ke kaʻina hana o ka hoʻohana ʻana i ka mea paia e kāʻei a hoʻopili paha i ka mea hana e pono ai ke hoʻokomo ʻia e hāʻawi i ke kākoʻo hana a i ʻole ka pale kemika. ʻO ka hoʻohana ʻana i ka ʻenehana hoʻokomo e hoʻopaʻa i ka cinnamaldehyde i loko o ka mea hoʻopili hiki ke hana i kona hoʻokuʻu lohi, hoʻomaikaʻi i ka helu paʻa, hoʻolōʻihi i ka ʻelemakule antibacterial o ke kiʻiʻoniʻoni, a hoʻonui i nā waiwai mechanical o ke kiʻiʻoniʻoni hoʻopili. I kēia manawa, hiki ke hoʻokaʻawale ʻia nā ʻano hana hana lawe maʻamau o ka hoʻohui ʻana i ka cinnamaldehyde me ke kiʻiʻoniʻoni hoʻopili i ʻelua mau māhele: ke kūkulu ʻana i ka mea lawe artificial a me ke kūkulu ʻana i ka mea lawe kūlohelohe, me ka hoʻokomo ʻana i ka polymer, ka hoʻokomo ʻana i ka nano liposome, ka hoʻokomo ʻana i ka cyclodextrin, ka hoʻopaʻa ʻana i ka nano clay a i ʻole ka hoʻouka ʻana. Ma o ka hui pū ʻana o ka papa hoʻākoakoa ponoʻī a me ka electrospinning, hiki ke hoʻonui ʻia ka mea lawe lawe cinnamaldehyde, a hiki ke hoʻomaikaʻi ʻia ke ʻano hana a me ka laulā o ka hoʻohana ʻana o ka cinnamaldehyde.

Ka hoʻohana ʻana i ka ʻili ʻili meaʻai hana cinnamon aldehyde

He ʻokoʻa ka nui o ka wai, ka haku mele ʻana o nā meaʻai a me nā kūlana mālama a me ka halihali o nā ʻano meaʻai like ʻole, a he ʻokoʻa loa ka ulu ʻana o nā microorganism spoilage. He ʻokoʻa nō hoʻi ka hopena mālama o ka cinnamaldehyde antibacterial packaging no nā meaʻai like ʻole.

1. Ka hopena mālama hou i nā mea kanu a me nā huaʻai

Ua waiwai ʻo Kina i nā kumuwaiwai kūlohelohe, a ma waena o ia mea he nui ka hana ʻana a me ka hoʻohana ʻana i nā mea kanu a me nā huaʻai ma ka mākeke. Eia nō naʻe, kiʻekiʻe ka wai a me ke kō o nā mea kanu a me nā huaʻai, waiwai i ka meaʻai, a hiki ke hoʻohaumia ʻia e nā microbial a me ka hōʻino ʻana i ka wā e mālama ai, lawe ʻia a kūʻai aku ai. I kēia manawa, ʻo ka hoʻopili ʻana i ka ʻili ʻōpala antibacterial kahi ala nui e hoʻomaikaʻi ai i ka mālama ʻana a me ka lawe ʻana i nā mea kanu a me nā huaʻai a hoʻolōʻihi i ko lākou ola papa. Hiki i ka ʻili ʻōpala cinnamaldehyde-polylactic acid composite o nā ʻāpala ke hōʻemi i ka nalowale o nā meaʻai, kāohi i ka ulu ʻana o nā rhizopus, a hoʻolōʻihi i ka manawa mālama o nā ʻāpala i 16 mau lā. I ka wā i hoʻopili ʻia ai ka ʻili ʻōpala meaʻai cinnamaldehyde i ka ʻōpala kāloti hou, ua kāohi ʻia ka ulu ʻana o ka ʻōpala a me ka hū, ua hoʻemi ʻia ka wikiwiki o ka pala o nā mea kanu, a ua hoʻolōʻihi ʻia ke ola papa i 12d.

2. Ka hopena mālama hou o nā huahana ʻiʻo He waiwai nui nā meaʻai ʻiʻo i ka protein, ka momona a me nā mea ʻē aʻe, waiwai i ka meaʻai a me ka ʻono kū hoʻokahi. I ka mahana o ka lumi, ʻo ka hana hou ʻana o nā microorganisms ke kumu o ka palaho ʻana o nā protein ʻiʻo, nā kalapona a me nā momona, e hopena ana i ka palaho o ka ʻiʻo, ka ʻili pipili, ke kala ʻeleʻele, ka nalowale o ka elasticity, a me ka ʻala ʻoluʻolu ʻole. Hoʻohana nui ʻia ka ʻili ʻai Cinnamaldehyde i ka ʻōpala puaʻa a me ka iʻa, kāohi nui i ka ulu ʻana o Staphylococcus aureus, Escherichia coli, aeromonas, yeast, lactic acid bacteria a me nā bacteria ʻē aʻe, a hiki ke hoʻolōʻihi i ke ola papa o 8 ~ 14d.

3. Ka hopena o ka mālama hou ʻana o nā huahana waiū I kēia manawa, ke piʻi nei ka hoʻohana ʻana i nā huahana waiū ma Kina i kēlā me kēia makahiki. He huahana waiū hū ʻia ka tīhi me ka waiwai nui o ka meaʻai a me ka protein. Akā, he pōkole ke ola o ka tīhi, a he mea hopohopo nō hoʻi ka nui o ka ʻōpala ma nā mahana haʻahaʻa. Hiki i ka hoʻohana ʻana i ka ʻili ʻili meaʻai cinnamic aldehyde ke hoʻolōʻihi i ke ola o ka tīhi, e hōʻoia i ka ʻono maikaʻi o ka tīhi, a pale i ka palaho ʻana o ka tīhi. No nā ʻāpana tīhi a me nā mea ʻono tīhi, ua hoʻolōʻihi ʻia ke ola o ka papa i 45 mau lā a me 26 mau lā ma hope o ka hoʻohana ʻana i ka cinnamaldehyde active packaging, kahi mea e kōkua ai i ka mālama ʻana i nā kumuwaiwai.

4. ʻO ka hopena mālama hou o ka berena a me ke keke meaʻai starch he mau huahana starch, i hana ʻia me ka hana palaoa huita, pulupulu paina palupalu, ʻono a ʻono. Eia nō naʻe, he pōkole ke ola o ka berena a me ke keke a he maʻalahi i ka haumia ʻana o ka ʻōpala i ka wā kūʻai aku, e hopena ana i ka hōʻino ʻana o ka maikaʻi a me ka ʻōpala meaʻai. ʻO ka hoʻohana ʻana i ka cinnamaldehyde active food packaging i loko o ka keke huʻahuʻa a me ka berena ʻokiʻoki hiki ke kāohi i ka ulu ʻana a me ka hoʻolaha ʻana o ka penicillium a me ka ʻōpala ʻeleʻele, a hoʻolōʻihi i ke ola o ka papa i 10 ~ 27d, kēlā me kēia.

 

Loaʻa i ka Cinnamaldehyde nā pono o ke kumu nui, ka bacteriostasis kiʻekiʻe a me ka haʻahaʻa o ka ʻawahia. Ma ke ʻano he mea bacteriostasis i loko o ka ʻōpala hana meaʻai, hiki ke hoʻomaikaʻi ʻia ke kūpaʻa a me ka hoʻokuʻu lohi o ka cinnamaldehyde ma ke kūkulu ʻana a me ka hoʻonui ʻana i ka mea lawe lawe, he mea nui ia no ka hoʻomaikaʻi ʻana i ka mālama ʻana a me ka lawe ʻana i ka meaʻai hou a me ka hoʻolōʻihi ʻana i ke ola papa o ka meaʻai. I nā makahiki i hala iho nei, ua hana ka cinnamaldehyde i nā hoʻokō he nui a me ka holomua i ka noiʻi ʻana i ka mālama ʻana i ka ʻōpala meaʻai, akā aia nō ka noiʻi noi pili i ke kahua mua, a aia nō kekahi mau pilikia e hoʻoponopono ʻia. Ma o ke aʻo hoʻohālikelike ʻana i nā hopena o nā mea lawe lawe like ʻole ma nā waiwai mechanical a me nā waiwai pale o ka membrane, ka ʻimi hohonu ʻana i ke ʻano o ka hana o ka cinnamaldehyde a me ka mea lawe a me kona kinetics hoʻokuʻu ʻana i nā wahi like ʻole, ke aʻo ʻana i ka mana o ke kānāwai ulu o nā microorganisms i ka meaʻai ma ka palaho meaʻai, a me ke ʻano hoʻoponopono o ka ʻōpala antibacterial i ka manawa a me ka wikiwiki o ka hoʻokuʻu ʻana o nā mea antimicrobial. Hoʻolālā a hoʻomohala i nā ʻōnaehana ʻōpala hana e hiki ke hoʻokō i nā koi mālama meaʻai like ʻole.