He mea ʻino anei ka phenoxyethanol i ka ʻili?

He aha ka meaphenoxyethanol?
ʻO ka Phenoxyethanol kahi glycol ether i hoʻokumu ʻia ma ka hoʻohui ʻana i nā hui phenolic me ka ethanol, a ʻike ʻia ia ma ke ʻano he ʻaila a mucilage paha i kona ʻano wai. He mea mālama maʻamau ia i nā mea hoʻonani, a hiki ke loaʻa i nā mea āpau mai nā kirīmi maka a i nā lotion.
Hoʻokō ka Phenoxyethanol i kona hopena mālama ʻaʻole ma o ka antioxidant akā ma o kāna hana anti-microbial, ka mea e kāohi a hoʻopau i nā nui o nā microorganism gram-positive a me nā microorganism maikaʻi ʻole. Loaʻa iā ia kahi hopena pale koʻikoʻi i nā ʻano bacteria maʻamau e like me E. coli a me Staphylococcus aureus.
He mea ʻino anei ka phenoxyethanol i ka ʻili?
Hiki i ka Phenoxyethanol ke make i ka wā e ʻai ʻia ai i nā nui he nui. Eia nō naʻe, ʻo ka hoʻopili ʻana o waho ophenoxyethanolma nā kiʻekiʻe ma lalo o 1.0% aia nō i loko o ka pae palekana.
Ua kūkākūkā mua mākou inā ua hoʻololi ʻia ka ethanol i acetaldehyde i ka nui ma ka ʻili a inā paha e komo nui ʻia e ka ʻili. He mea nui loa kēia mau mea ʻelua no ka phenoxyethanol. No ka ʻili me kahi pale paʻa, ʻo ka phenoxyethanol kekahi o nā glycol ethers e hoʻohaʻahaʻa wikiwiki loa. Inā like ke ala metabolic o ka phenoxyethanol me ko ka ethanol, ʻo ka hana aʻe ka hoʻokumu ʻia ʻana o ka acetaldehyde paʻa ʻole, ukali ʻia e ka phenoxyacetic acid a me nā radical manuahi ʻē aʻe.
Mai hopohopo! I ko mākou kūkākūkā ʻana i ka retinol ma mua, ua ʻōlelo pū mākou i ka ʻōnaehana enzyme e pili ana i ka metabolism ophenoxyethanol, a ʻo kēia mau kaʻina hana hoʻololi e hana ʻia ma lalo o ka stratum corneum. No laila pono mākou e ʻike i ka nui o ka phenoxyethanol i hoʻopili maoli ʻia ma ke ʻano transdermal. Ma kekahi noiʻi i hoʻāʻo i ka omo ʻana o kahi sealant wai e loaʻa ana ka phenoxyethanol a me nā mea anti-microbial ʻē aʻe, ʻo ka ʻili puaʻa (nona ka permeability kokoke loa i nā kānaka) e omo i ka 2% phenoxyethanol, kahi i hoʻonui ʻia i 1.4% wale nō ma hope o 6 mau hola, a me 11.3% ma hope o 28 mau hola.
Hōʻike kēia mau haʻawina i ka omo ʻana a me ka hoʻololi ʻana ophenoxyethanolma nā ʻāpana i emi iho ma mua o 1% ʻaʻole lawa ke kiʻekiʻe e hana i nā dosis ʻino o nā metabolites. Ua loaʻa pū nā hopena like i nā haʻawina e hoʻohana ana i nā pēpē hānau hou ma lalo o 27 mau pule. Ua ʻōlelo ka haʻawina, "Aqueousphenoxyethanolʻaʻole ia e hōʻino nui i ka ʻili i hoʻohālikelike ʻia me nā mea mālama ethanol. Hoʻopili ʻia ka Phenoxyethanol i loko o ka ʻili o nā pēpē hānau hou, akā ʻaʻole ia e hana i ka huahana oxidation phenoxyacetic acid i nā nui nui." Hōʻike pū kēia hopena ʻo ka phenoxyethanol ka nui o ka metabolism i loko o ka ʻili a ʻaʻole ia e hōʻino nui. Inā hiki i nā pēpē ke lawelawe iā ia, he aha kāu e makaʻu ai?
ʻO wai ka mea ʻoi aku ka maikaʻi, phenoxyethanol a i ʻole ka waiʻona?
ʻOiai ua wikiwiki ka metabolized ʻana o ka phenoxyethanol ma mua o ka ethanol, ʻoi aku ka haʻahaʻa o ka nui i kaupalena ʻia no ka hoʻopili ʻana ma ka topical ma 1%, no laila ʻaʻole ia he hoʻohālikelike maikaʻi. ʻOiai ke pale nei ka stratum corneum i ka hapa nui o nā molekala mai ka omo ʻia ʻana, ʻoi aku ka liʻiliʻi o nā radical manuahi i hana ʻia e kēia mau mea ʻelua ma mua o nā mea i hana ʻia e kā lākou mau hopena oxidation ponoʻī i kēlā me kēia lā! Eia kekahi, no ka mea aia nā hui phenolic i loko o ka phenoxyethanol ma ke ʻano o ka ʻaila, evaporate a maloʻo lohi.
Hōʻuluʻulu manaʻo
He mea mālama maʻamau ka Phenoxyethanol i hoʻohana ʻia i nā mea hoʻonani. He palekana a he pono hoʻi, a ʻo ia ka lua ma hope o nā parabens ma ke ʻano o ka hoʻohana ʻana. ʻOiai ke manaʻo nei au he palekana nō hoʻi nā parabens, inā ʻoe e ʻimi nei i nā huahana me ka ʻole o nā parabens, he koho maikaʻi ka phenoxyethanol!