ʻO ka Pharmacodynamics o Chloroxylenol

Chloroxylenol, a i ʻole para-chloro-meta-xylenol (PCMX), he mea antibacterial a sterilizing kaulana ia. He mea hoʻomaʻemaʻe ia i hoʻohana ʻia ma ka hale keaka haukapila e hoʻomaʻemaʻe i nā pahu hana ʻoki.

ʻO Chloroxylenol kekahi o nā mea hana i hoʻohana ʻia i ka hana ʻana i nā kopa antiseptic. Eia kekahi, ua ʻoki ʻia kāna mau noi ma ke ʻano he disinfectant ma nā lāʻau lapaʻau a me nā mea kūloko.

Wahi a ka Papa Inoa o nā Lāʻau Lapaʻau Koʻikoʻi a ka World Health Organization, ua palapala maikaʻi ʻia ka pilikia o ka chloroxylenol i ke ʻano bacteria i ʻike ʻia ʻo Gram-positive.

Eia nō naʻe, inā ʻoe e pono i kahi mea antibacterial a me disinfectant maikaʻi no kou home a me nā pono o ka haukapila, a laila pono ʻoe e hoʻokaʻaʻike aku i kahi mea hilinaʻikloroksilenolmea hana.

Hōʻailona lāʻau lapaʻau o Chloroxylenol

Ua ʻike nui ʻia nā hoʻohana ʻana o Chloroxylenol ma ke kahua lapaʻau.

Ua hoʻohana mua ʻia ia i ka mālama ʻana i nā maʻi ʻili e like me nā ʻōpala, nā ʻoki, nā nahu holoholona, ​​​​nā ʻaki, a me ka mea hoʻomaʻemaʻe lima.

ʻO ka Pharmacodynamics o Chloroxylenol

Chloroxylenolhe phenol pani, ʻo ia hoʻi he hui hydroxyl kona i loko o kona ʻano.

Ua ʻike maikaʻi ʻia kona hoʻohana ʻana i nā makahiki he nui ma ke ʻano he hoʻokahi o nā mea hana o nā huahana pepehi germs. Manaʻo ʻia kona hoʻohana ʻana ma waho o ke kelepona.

Ua hōʻike ʻia kāna hana antimicrobial ma kahi liʻiliʻi i kahi hui o nā bacteria.

ʻAno Hana

He mea nui loa ka hele ʻana o nā hui hydroxyl i loko o kona ʻano, ʻoiai ke wehewehe ʻia kona hiki ke hana i nā hana pharmacological.

Ua manaʻo ʻia ka hui hydroxyl e hoʻopili i nā wahi hoʻopaʻa o ka protein, ʻo ia hoʻi, e kōkua i ka pale ʻana i ka bacteria āna e hoʻouka ai.

Komo ʻo Chloroxylenol i loko o ke kelepona bacteria e hoʻouka hou aku me nā enzymes a me nā protein lawa. Ke hana ʻia kēia, hoʻopau ia i nā hana o ke kelepona.

E hōʻea ia i kahi pae kahi e hoʻopili ʻia ai ka nui o Chloroxylenol i nā ʻāpana clot e hopena ai i ko lākou make.

Ka Metabolism o Chloroxylenol

No ka palapala pono ʻana o Chloroxylenol ma ke ʻano he mea bacteria a me ka mea hoʻomaʻemaʻe, ua hoʻohana ʻia nā holoholona e aʻo piha i ka hana o kona mau hiki.

Ua hōʻike ʻia ka hoʻāʻo holoholona ma muli o ka hoʻohana ʻana i ka ʻili o Chloroxylenol, ua wikiwiki loa ka wikiwiki o ka hoʻokomo ʻana i loko o nā hola ʻelua mua.

Ua ʻike ʻia hoʻi ua mimi ʻia ka mea i hāʻawi ʻia i nā holoholona ma o ka puʻupaʻa me ka hoʻohemo piha ʻana i ka wikiwiki o 24 mau hola.

ʻO ka mea nui i ʻike ʻia i loko o ka hāpana i hoʻopau ʻia e komo pū me nā glucuronides a me nā sulfates.

Ua hoʻohālikelike ka hapa nui o nā ʻatikala noiʻi e pili ana iā Chloroxylenol i kāna hana me ka triclosan, kahi lāʻau antibacterial kaulana a mahalo nui ʻia. Ua hōʻike ka hōʻike he ʻāpana pū kekahi o nā glucuronides o ka hāpana i hoʻokahe ʻia i loko o ke kumu hoʻohālike kanaka.

ʻOi aku hoʻi, mai ke aʻo ʻana o ke kumu hoʻohālike kanaka, ua manaʻo ʻia ʻo kēlā me kēia 5 mg i lawe ʻia i loko o ke kino e mimi a hiki i ka 14% o ka waikawa glucuronic a me ka waikawa sulfuric i loko o ʻekolu lā.

Eia nō naʻe, ʻo kekahi nui o Chloroxylenol i lawe ʻia i loko o ka ʻōnaehana e hoʻoheheʻe ʻia e ke akepaʻa a mimi ʻia i waho ma ke ʻano he sulfate a me nā mea i loaʻa i ka glucuronic.

Ala o ka Hoʻopau ʻana

E like me ka mea i ʻike ʻia ma luna mai nā haʻawina i mālama ʻia me Chloroxylenol e hōʻike ana ʻo ke ala nui e wehe ʻia ai ka chloroxylenol mai ka ʻōnaehana ma hope o ka hoʻokele ʻana ma o ka mimi.

ʻOiai, ua manaʻo ʻia he mea liʻiliʻi loa ka nui i loko o ka bile a he mea liʻiliʻi loa i ka ea hanu.

Pono ʻoe i ka Chloroxylenol?

Me ka lokomaikaʻikaomi ma aneʻii kēia lā noChloroxylenolno kāu mau huahana antiseptic a me disinfectant āpau, a e hauʻoli nui mākou e hui pū me ʻoe no nā huahana maikaʻi loa.