Formaldehyde a me glutaraldehydeʻO nā mea hana kemika ʻelua i hoʻohana ʻia ma ke ʻano he crosslinking agents i nā noi like ʻole, ʻoi aku hoʻi i nā kula o ka biology, chemistry, a me nā ʻepekema waiwai.ʻOiai lawelawe lākou i nā kumu like i ka crosslinking biomolecules a me ka mālama ʻana i nā specimen biological, loaʻa iā lākou nā waiwai kemika ʻokoʻa, reactivity, toxicity, a me nā noi.
Nā mea like:
Nā Agena Crosslinking: Formaldehyde a mehe mau aldehydes ka glutaraldehyde, 'o ia ho'i he hui kalapona ko lākou (-CHO) ma ka hope o ko lākou ho'olālā mole.ʻO kā lākou hana nui ka hana ʻana i nā paʻa covalent ma waena o nā pūʻulu hana o nā biomolecules, ka hopena i ka crosslinking.Pono ka hoʻopili ʻana no ka hoʻopaʻa ʻana i ke ʻano o nā laʻana olaola, e ʻoi aku ka paʻa a paʻa i ka pōʻino.
Nā noi lāʻau lapaʻau: Loaʻa i ka formaldehyde a me ka glutaraldehyde ka hoʻohana nui ʻana i ka hana biomedical.Hoʻohana pinepine ʻia lākou no ka hoʻopaʻa ʻana a me ka mālama ʻana i ka histology a me nā haʻawina pathology.Mālama nā ʻiʻo i hoʻopaʻa ʻia i ko lākou kūpaʻa ʻana a hiki ke hana hou ʻia no nā kumu analytical a diagnostic.
Ka Manaʻo Microbial: Loaʻa i nā mea ʻelua nā waiwai antimicrobial, e hoʻolilo iā lākou i mea waiwai i ka disinfection a me nā kaʻina sterilization.Hiki iā lākou ke hoʻopau i ka maʻi bacteria, nā maʻi maʻi, a me nā haʻiki, e hōʻemi ana i ka pilikia o ka hoʻohaumia ʻana i nā hoʻonohonoho hoʻokolohua a me nā mea lapaʻau.
No Hana Hana: formaldehyde a meglutaraldehydehoʻohana ʻia i nā noi ʻoihana like ʻole.Hoʻohana ʻia lākou i ka hana ʻana i nā adhesives, resins, a me nā polymers, a me nā ʻoihana ʻili a me nā lole.
Nā ʻokoʻa:
Ke Kino Hana: ʻO ka ʻokoʻa mua ma waena o ka formaldehyde a me ka glutaraldehyde aia i loko o kā lākou mau molekala.ʻO Formaldehyde (CH2O) ka aldehyde maʻalahi loa, i haku ʻia me hoʻokahi ʻātoma kalapona, ʻelua mau mana hydrogen, a hoʻokahi ʻātoma oxygen.ʻO Glutaraldehyde (C5H8O2), ma ka ʻaoʻao ʻē aʻe, he aldehyde aliphatic ʻoi aku ka paʻakikī, nona nā ʻātoma kalapona ʻelima, ʻewalu mau mana hydrogen, a me ʻelua mau mana oxygen.
ʻO ka hana hou: ʻoi aku ka ʻoi aku o ka glutaraldehyde ma mua o ka formaldehyde ma muli o kona kaulahao kalapona lōʻihi.ʻO ka loaʻa ʻana o ʻelima mau kalapona kalapona i ka glutaraldehyde hiki iā ia ke hoʻopaʻa i nā mamao lōʻihi ma waena o nā pūʻulu hana ma nā biomolecules, e alakaʻi ana i ka crosslinking wikiwiki a ʻoi aku ka maikaʻi.
ʻOi aku ka maikaʻi o ka glutaraldehyde i ka hoʻopili ʻana i nā biomolecules nui, e like me nā protein a me nā enzymes.ʻO ka Formaldehyde, ʻoiai hiki ke hoʻopaʻa ʻia, pono paha i ka manawa a i ʻole ka ʻoi aku ka nui o ka ʻike e loaʻa ai nā hopena like me nā molekala nui.
ʻAiʻona: Ua ʻike ʻia ʻo Glutaraldehyde i ʻoi aku ka ʻona ma mua o ka formaldehyde.Hiki i ka glutaraldehyde lōʻihi a i ʻole koʻikoʻi ke hoʻoulu i ka ʻili a me ka hanu ʻana, a manaʻo ʻia he sensitizer, ʻo ia hoʻi hiki ke alakaʻi i nā hopena maʻi i kekahi poʻe.ʻO ka ʻokoʻa, ʻo ka formaldehyde kahi mea make kino kaulana a loaʻa i nā pōʻino olakino, ʻoiai ke hoʻohu ʻia a i ʻole ka pili ʻana me ka ʻili.
Hoʻohana: ʻOiai ua hoʻohana ʻia nā kemika ʻelua i ka hoʻoponopono ʻana i nā kiko, makemake pinepine ʻia lākou no nā kumu like ʻole.Hoʻohana maʻamau ka formaldehyde no nā noi histological maʻamau a me ka embalming, ʻoiai ʻoi aku ka maikaʻi o ka glutaraldehyde no ka mālama ʻana i nā hale kelepona a me nā pae antigenic i ka microscopy electron a me nā haʻawina immunohistochemical.
Paʻa: ʻoi aku ka maʻalahi o ka formaldehyde a ʻoi aku ka wikiwiki o ka evaporate ma mua o ka glutaraldehyde.Hiki i kēia waiwai ke hoʻololi i ka mālama ʻana a me ka mālama ʻana i nā koi o nā mea hoʻohui crosslinking.
I ka hōʻuluʻulu manaʻo, kaʻana like ka formaldehyde a me ka glutaraldehyde i nā ʻano maʻamau ma ke ʻano he mau mea hoʻohui crosslinking, akā ʻokoʻa loa lākou i kā lākou mau hana kemika, ka hoʻoulu ʻana, nā mea ʻawaʻawa, a me nā noi.He mea nui ka hoʻomaopopo pono ʻana i kēia mau ʻokoʻa no ke koho ʻana i ka mea hana crosslinking kūpono no nā kumu kikoʻī a me ka hōʻoia ʻana i ka palekana a me ka hoʻohana pono ʻana i nā ʻano ʻepekema, lāʻau lapaʻau, a me ka ʻenehana.
Ka manawa hoʻouna: Iulai-28-2023