Ua ʻike mua ʻia ʻo ia ʻo "whitening gula", a aia kona kaulana i kona hopena keʻokeʻo like ʻole ma kekahi ʻaoʻao, a ʻo ka paʻakikī a me ka liʻiliʻi o kāna unuhi ʻana ma kekahi ʻaoʻao.ʻO ka mea kanu ʻo Glycyrrhiza glabra ke kumu o Glabridin, akā ʻo Glabridin wale nō ka helu no 0.1%-0.3% o kāna ʻike holoʻokoʻa, ʻo ia hoʻi, hiki i ka 1000kg o Glycyrrhiza glabra ke loaʻa i 100g wale nō.ʻO Glabridin, Ua like ka 1g o Glabridin me 1g o ke gula kino.
ʻO Hikarigandine kahi ʻelele maʻamau o nā mea kanu lāʻau, a ʻike ʻia kona hopena keʻokeʻo e Iapana
ʻO Glycyrrhiza glabra kahi mea kanu o ka genus Glycyrrhiza.ʻO Kina ka ʻāina me ka waiwai o nā mea ulu lāʻau ma ka honua, a ʻoi aku ma mua o 500 mau ʻano lāʻau i hoʻohana ʻia i ka hoʻomaʻamaʻa lapaʻau, ʻo ia ka mea i hoʻohana nui ʻia he licorice.Wahi a nā helu helu, ʻoi aku ka nui o ka hoʻohana ʻana i ka licorice ma luna o 79%.
Ma muli o ka mōʻaukala lōʻihi o ka noi, i hele pū ʻia me kahi kūlana kiʻekiʻe, ʻaʻole i haki wale ka laulā o ka noiʻi ʻana i ka waiwai o ka licorice i nā palena ʻāina, akā ua hoʻonui ʻia ka noi.Wahi a ka noiʻi, mahalo nui nā mea kūʻai ma Asia, ʻoi aku hoʻi ma Iapana i nā mea hoʻonaninani i loaʻa nā mea kanu lāʻau.Ua ho'opa'a 'ia he 114 mau mea ho'oma'ema'e lā'au ma loko o ka "Iapana's General Cosmetics Raw Materials", a he 200 mau 'ano mea ho'oma'ema'e i loa'a nā mea kanu lā'au ma Iapana.
Ua ʻike ʻia he hopena keʻokeʻo super, akā he aha nā pilikia i ka hoʻohana pono?
Aia ka ʻāpana hydrophobic o ka licorice extract i nā ʻano flavonoids.Ma ke ʻano nui o kāna ʻāpana hydrophobic, ʻo halo-glycyrrhizidine ka hopena inhibitory i ka hana melanin a loaʻa pū kekahi i nā hopena anti-inflammatory a anti-oxidant.
Hōʻike kekahi mau ʻikepili hoʻokolohua ʻo ka hopena keʻokeʻo o Glabridin māmā he 232 mau manawa kiʻekiʻe ma mua o ka huaora C maʻamau, 16 mau manawa kiʻekiʻe ma mua o ka hydroquinone, a he 1,164 mau manawa kiʻekiʻe ma mua o ka arbutin.Pehea e hoʻokō ai i ka hana keʻokeʻo ikaika, hāʻawi ʻo Glabridin māmā i ʻekolu mau ala like ʻole.
1. Kāohi i ka hana tyrosinase
Ke kumu whitening mechanical oʻO GlabridinʻO ia ke kāohi i ka synthesis o ka melanin ma o ka hoʻokūkū hoʻokūkū i ka hana tyrosinase, ka lawe ʻana i ka ʻāpana o ka tyrosinase mai ke apo catalytic o ka melanin synthesis a pale i ka hoʻopaʻa ʻana o ka substrate i tyrosinase.
2. Ka hopena antioxidant
Hiki iā ia ke pale i ka hana o tyrosinase a me dopa pigment interchange a me ka hana o ka dihydroxyindole carboxylic acid oxidase.
Ua hōʻike ʻia ma kahi ʻano o 0.1mg / ml, hiki i ka photoglycyrrhizidine ke hana ma ka cytochrome P450 / NADOH oxidation system a scavenge 67% o nā radical manuahi, nona ka hana antioxidant ikaika.
3.Inhibit nā mea inflammatory a hakakā me UV
I kēia manawa, ua hōʻike ʻia ka liʻiliʻi o ka noiʻi e pili ana i ka hoʻohana ʻana i ka photoglycyrrhizidine i ke aʻo ʻana i ke kiʻi ʻili i hoʻoiho ʻia e UV.I ka makahiki 2021, i loko o kahi ʻatikala i loko o ka puke moʻolelo koʻikoʻi Journal of Microbiology and Biotechnology, ua aʻo ʻia nā liposomes photoglycyrrhizidine no ko lākou hiki ke hoʻomaikaʻi i ka erythema a me ka maʻi ʻili o ka ʻili ma o ka pale ʻana i nā mea inflammatory.Hiki ke hoʻohana ʻia nā liposomes Photoglycyrrhizidine no ka hoʻomaikaʻi ʻana i ka bioavailability me ka liʻiliʻi o ka cytotoxicity me ka ʻoi aku ka maikaʻi o ka melanin inhibition, e hōʻemi pono ana i ka hōʻike ʻana o nā cytokines inflammatory, interleukin 6 a me interleukin 10. No laila, hiki ke hoʻohana ʻia ma ke ʻano he lāʻau lapaʻau topical e pale aku i ka pōʻino o ka ʻili o ka radiation UV. ma ke kaohi ʻana i ka mumū, hiki ke hāʻawi i kekahi mau manaʻo no ka noiʻi ʻana i nā huahana pale keʻokeʻo o ka lā.
I ka hōʻuluʻulu manaʻo, ʻike ʻia ka hopena keʻokeʻo o ka photoglycyrrhizidine, akā ʻo kona ʻano ponoʻī he aneane hiki ʻole ke hoʻoheheʻe ʻia i ka wai, no laila ua koi nui ʻia no ka hana ʻana a me ke kaʻina hana i ka noi ʻana o ka hoʻohui ʻana i ka ʻili, a he hopena maikaʻi ia ma o ka liposome. ʻenehana encapsulation.Eia kekahi, kiʻiʻO GlabridinHiki i nā liposomes ke pale i nā kiʻi kiʻi UV, akā pono kēia hana i nā hoʻokolohua lapaʻau hou aʻe e hōʻoia ʻia a hoʻokō ʻia nā noi noiʻi.
ʻO nā huahana mālama ʻili i loaʻa ka photoGlabridin ma ke ʻano o ka hui pū ʻana.
ʻOiai ʻaʻohe kānalua he hopena keʻokeʻo maikaʻi loa ka photoGlabridine, ua pāpā ʻia ke kumu kūʻai kumu waiwai ma muli o ka paʻakikī o ka unuhi a me ka ʻike.I ka cosmetic R&D, pili pono ka hana o ka hoomalu ana i na koina i ka ma'i'o 'enehana a me ke ka'ina 'epekema.No laila, he ala maikaʻi ia e hoʻomalu ai i ke kumukūʻai o nā formulations a e hoʻokō i ka maikaʻi palekana a maikaʻi hoʻi ma ke koho ʻana i nā mea hana a hoʻohui iā lākou i ka hui pū ʻana me photoglycyrrhizidine.Ma waho aʻe o ka pae R&D, pono ka ʻimi hou ʻana e pili ana i ka noiʻi ʻana i nā liposomes photoglycyrrhizidine a me nā ʻenehana hou loa.
Ka manawa hoʻouna: ʻAukake-30-2022