He aha nā hoʻohana nui o ka triclosan?

ʻO Triclosanhe antimicrobial ākea ākea i hoʻohana ʻia ma ke ʻano he antiseptic, disinfectant a preservative paha i nā wahi lapaʻau, nā huahana mea kūʻai like ʻole e like me nā mea hoʻonani, nā huahana hoʻomaʻemaʻe hale, nā mea plastik, nā mea pāʻani, nā pena, a pēlā aku. Hoʻohui pū ʻia ia ma luna o ka ʻili o nā mea lapaʻau, nā mea plastik, nā lole, nā lako kīhini, a pēlā aku, kahi e hiki ai ke lele mālie no ka manawa lōʻihi i ko lākou hoʻohana ʻana, e hana i kāna hana biocidal.

Pehea e hoʻohana ʻia ai ka triclosan i nā mea hoʻonani?

ʻO Triclosanua helu ʻia i ka makahiki 1986 ma ka European Community Cosmetics Directive no ka hoʻohana ʻana ma ke ʻano he mea mālama i nā huahana hoʻonani ma nā ʻano a hiki i ka 0.3%. Ua hoʻoholo ka loiloi pilikia hou i hana ʻia e ka EU Scientific Committee on Consumer Products, ʻoiai ʻo kona hoʻohana ʻana ma kahi ʻano kiʻekiʻe o 0.3% i nā toothpastes, nā kopa lima, nā kopa kino/nā gel ʻauʻau a me nā lāʻau deodorant ua manaʻo ʻia he palekana ma kahi ʻano toxicological i nā huahana pākahi, ʻaʻole palekana ka nui o ka hōʻike ʻana i ka triclosan mai nā huahana hoʻonani āpau.

Ua manaʻo ʻia he palekana kekahi hoʻohana hou ʻana o ka triclosan i nā pauka maka a me nā mea hūnā kīnā ma kēia ʻano nui, akā ʻaʻole i manaʻo ʻia he palekana no ka mea kūʻai aku ka hoʻohana ʻana o ka triclosan i nā huahana waiho ʻē aʻe (e like me nā lotion kino) a me nā holoi waha ma muli o nā hōʻike kiʻekiʻe i loaʻa. ʻAʻole i loiloi ʻia ka ʻike ʻana i ka triclosan mai nā huahana pīpī (e like me nā deodorants).

ʻO Triclosanʻoiai ʻaʻole ionic, hiki ke hoʻohui ʻia i loko o nā dentifrices maʻamau. Eia nō naʻe, ʻaʻole ia e hoʻopaʻa i nā ʻili waha no nā hola he nui, a no laila ʻaʻole ia e hāʻawi i kahi pae mau o ka hana anti-plaque. No ka hoʻonui ʻana i ka lawe ʻana a me ka paʻa ʻana o ka triclosan e nā ʻili waha no ka hoʻomaikaʻi ʻana i ka kaohi plaque a me ke olakino gingival, hoʻohana ʻia ka triclosan/polyvinylmethyl ether maleic acid copolymer a me ka triclosan/zinc citrate a me ka triclosan/calcium carbonate dentifrice.

Pehea e hoʻohana ʻia ai ka triclosan i nā mea mālama ola kino a me nā mea lapaʻau?

ʻO Triclosanua hoʻohana pono ʻia ma ke ʻano lapaʻau e hoʻopau i nā micro-organism e like me ka methicillin-resistant Staphylococcus aureus (MRSA), ʻoiai me ka ʻōlelo aʻoaʻo e hoʻohana i ka ʻauʻau triclosan 2%. Hoʻohana ʻia ʻo Triclosan ma ke ʻano he ʻōpala ʻokiʻoki, a hoʻohana nui ʻia ia i ka holoi lima a me ke ʻano he holoi kino e hoʻopau iā MRSA mai nā mea lawe ma mua o ke ʻoki ʻana.

Hoʻohana ʻia ʻo Triclosan i loko o kekahi mau mea lapaʻau, no ka laʻana, nā stent ureteral, nā sutures ʻokiʻoki a hiki ke manaʻo ʻia e pale aku i ka maʻi graft. ʻAʻole i ʻike ʻo Bojar et al i kahi ʻokoʻa i ka colonization ma waena o nā sutures i uhi ʻia e triclosan a me ka suture multifilament maʻamau, ʻoiai ʻo kā lākou hana e pili ana i ʻelima mau bacteria a ua hoʻokumu wale ʻia ma ka hoʻoholo ʻana o ka zone of inhibition.

I loko o nā stents ureteral, ua hōʻike ʻia ka triclosan e kāohi i ka ulu ʻana o nā uropathogens bacteria maʻamau a e hōʻemi i ka nui o nā maʻi urinary-tract a, hiki paha, ua hōʻike hou ka catheter encrustation i nā hopena synergistic o triclosan a me nā antibiotics pili i nā isolates clinical e pili ana i ʻehiku mau ʻano uropathogenic, a kākoʻo lākou i ka hoʻohana ʻana i ka stent triclosan-eluting i ka wā e pono ai, me ka lāʻau antibiotic maʻamau i ka mālama ʻana i nā maʻi paʻakikī.

Ma kekahi mau hoʻomohala hou aʻe, ua manaʻo ʻia ka hoʻohana ʻana o ka triclosan i loko o ka urinary Foley catheter ʻoiai ua kāohi pono ʻo triclosan i ka ulu ʻana o Proteus mirabilis a kāohi i ka encrustation a me ka blockaction o ka catheter. I kēia manawa, ua hōʻike ʻo Darouiche et al. i ka hana synergistic, broad-spectrum a me ka paʻa antimicrobial o nā catheters i uhi ʻia me ka hui pū ʻana o triclosan a me DispersinB, kahi enzyme anti-biofilm e kāohi a hoʻopuehu i nā biofilms.

Pehea e hoʻohana ʻia ai ka triclosan i nā huahana mea kūʻai aku ʻē aʻe?

ʻO ka hana antimicrobial ākea o ka triclosan ua alakaʻi i kona hoʻokomo ʻia ʻana i loko o kahi ākea o nā ʻano huahana i manaʻo ʻia no ka hoʻohana ʻana i ka home e like me nā kopa wai, nā detergents, nā papa ʻokiʻoki, nā mea pāʻani a nā keiki, nā kāpeti a me nā ipu mālama meaʻai. Hāʻawi ʻia kahi papa inoa kikoʻī o nā huahana mea kūʻai aku i loaʻa ka triclosan e ka US Environmental Protection Agency (EPA) a e nā NGO US "Environmental Working Group" a me "Beyond Pesticides".

Ke hoʻonui nei ka nui o nā mea lole i mālama ʻia me nā biocides. ʻO Triclosan kekahi o nā mea hoʻopau no ka hana ʻana o ia mau lole. Hoʻopau ʻia nā lole i hoʻopau ʻia me ka triclosan me nā mea hoʻopili e hāʻawi i nā waiwai antibacterial paʻa. Ma ke kumu o ka ʻike i loaʻa, ua kālailai ʻia he 17 mau huahana mai ka mākeke kūʻai kūʻai Denemaka no ka ʻike o kekahi mau hui antibacterial i koho ʻia: triclosan, dichlorophen, Kathon 893, hexachlorophen, triclocarban a me Kathon CG. Ua ʻike ʻia he ʻelima o nā huahana i loaʻa he 0.0007% - 0.0195% triclosan.

Ma ka loiloi ʻōnaehana mua a Aiello et al. e loiloi ana i ka pono o nā kopa i loaʻa ka triclosan, ua loiloi ʻo ia i 27 mau haʻawina i paʻi ʻia ma waena o 1980 a me 2006. ʻO kekahi o nā ʻike koʻikoʻi, ʻo nā kopa i loaʻa ka triclosan ma lalo o 1% ʻaʻole i hōʻike i ka pono mai nā kopa non-antimicrobial. Ua hōʻike nā haʻawina i hoʻohana i ke kopa i loaʻa ka > 1% triclosan i ka emi nui ʻana o nā pae bacteria ma ka lima, pinepine ma hope o nā noi he nui.

ʻO ka nele o ka pilina ma waena o ka hoʻohana ʻana i ke kopa me ka triclosan a me ka emi ʻana o ka maʻi lele ua paʻakikī ke ʻike pono i ka ʻike ʻole ʻia ʻana o nā mea olaola nāna e kuleana no nā hōʻailona o ka maʻi. Ua hōʻike ʻia ʻelua mau noiʻi US hou loa ua hōʻemi ka holoi lima me ke kopa antimicrobial me ka triclosan (0.46%) i ka ukana bacteria a me ka hoʻoili ʻana o ka bacteria mai nā lima, i hoʻohālikelike ʻia me ka holoi lima me ke kopa non-antimicrobial.

Nā Huahana Puna

Hana mākou i nā ʻano huahana like ʻole e hiki ke hoʻohana ʻia i ka mālama pilikino a me ka ʻoihana hoʻonani, e like me ka mālama ʻili, ka mālama lauoho, ka mālama waha, nā mea hoʻonani, ka hoʻomaʻemaʻe hale, ka mālama ʻana i ka mea holoi a me ka holoi lole, ka hoʻomaʻemaʻe haukapila a me nā hale lehulehu. E kāhea mai iā mākou i kēia manawa inā ʻoe e ʻimi nei i kahi hoa ʻoihana hilinaʻi.